Study shows few serious problems among smallpox vaccinees

first_imgDec 14, 2005 (CIDRAP News) – Exactly 100 of about 38,000 civilians who received smallpox shots in a federal program in 2003 suffered serious adverse events afterward, signaling that the program successfully screened out most people at risk for complications, according to a recent report.The safety monitoring system “achieved its goal of safe administration of smallpox vaccine among a limited number of DHHS [Department of Health and Human Services] volunteers through successful exclusion of at-risk individuals and rapid detection of unexpected adverse events,” says the report, published in the Dec 7 Journal of the American Medical Association.The authors, with the Centers for Disease Control and Prevention (CDC), analyzed adverse events reported as a result of the smallpox vaccination program from January through October of 2003. HHS launched the program for healthcare and emergency response workers out of concern about the possibility of a terrorist release of smallpox virus. The report’s first author is Christine G. Casey, MD, of the CDC’s National Immunization Program.Authorities originally hoped to vaccinate as many as 500,000 health workers, but only 37,901 received shots by the end of October 2003. Hospital and public health workers constituted 95% of those, with law enforcement and firefighters making up most of the rest, the report says. Most of the vaccinees (64%) were women, and more than 75% of them were between 40 and 64 years old and had received a smallpox shot before.The Vaccine Adverse Event Reporting System (VAERS) received 822 adverse-event reports related to the vaccinations, the report says. Of these, 100 were classified as serious events, for a rate of 26.4 per 10,000 vaccinees.Of the 100 serious events, 85 involved hospitalization or prolongation of hospitalization. Two people suffered permanent disability, and 10 experienced a life-threatening illness. The serious events included 21 classified as myopericarditis and 10 classified as ischemic events that were not expected on the basis of patient histories. Those 10 included six myocardial infarctions, two of which were fatal, and four cases of new or increased angina. Two cases of dilated cardiomyopathy occurring 2 to 3 months after vaccination were also reported.As a result of cardiac adverse events in both civilian and military smallpox vaccinees, the CDC issued a Health Alert Notice on Mar 26, 2003, that described the events and recommended deferring vaccination for at-risk people. None of the 10 ischemic cardiac events in vaccinees occurred after the alert notice triggered cardiac screening of potential vacccinees, the report says.The authors note that US military personnel recently vaccinated against smallpox have had a significantly increased rate of myocarditis, compared with unvaccinated military members. However, the report says the rate of ischemic cardiac events in civilian vaccinees does not appear to exceed the rate in a comparable unvaccinated population.”Whether smallpox vaccination is causally associated with ischemic events remains uncertain,” the authors write.Two cases of generalized vaccinia and one case of postvaccinial encephalitis were reported in the program. But there were no cases of transmission of vaccinia (the vaccine virus) to others and no severe reactions requiring treatment with vaccinia immune globulin.Among the 722 “nonserious” adverse events reported, the most common signs and symptoms were fever, 18.9%; rash, 18.4%; pain, 16.0%; headache, 15.2%; fatigue, 13.5%; and pruritus, 13.4%. Compared with those reporting nonserious events, people reporting serious events were more likely to be older than 40 (81% versus 64%).People who had been vaccinated previously were slightly overrepresented among the vaccinees with serious adverse events, the authors found. They say this is not surprising, since the revaccinees were older than the primary vaccinees and may have had a higher risk of adverse events because of age-related underlying chronic disease.The rates of expected, preventable, and noncardiac adverse events in the civilian vaccinees were about the same as rates in the much larger military vaccination program, the authors found.Casey CG, Iskander JK, Roper MH, et al. Adverse events associated with smallpox vaccination in the United States, January-October 2003. JAMA 2005 Dec 7;294(21):2734-43 [Abstract]See also:Safety summary for Department of Defense smallpox vaccination programhttp://www.smallpox.mil/event/SPSafetySum.asplast_img read more

The winter senior program brings 30 guests from Scandinavia and Germany to Dubrovnik

first_imgWith a large number of destinations that are regularly connected to Dubrovnik during the winter, from Monday, January 14, begins the charter program of arrivals of senior groups from Scandinavia and Germany, which will bring over 11 visitors to Dubrovnik by May 30. This prolongs the season, the length of stay of guests, increases tourist spending and satisfaction with the destination, as well as the key problem of mass tourism that is present in Dubrovnik. This is called strategic and sustainable development, not that Dubrovnik sees only itself and within its “four” walls. OVER 30 THOUSAND VISITORS FROM SCANDINAVIA AND GERMANY Photo: Pixabay.com An excellent program and an example of how the season is extended, ie in this case we can talk about a high pre-season. Also, it should be praised that Dubrovnik is a place of arrival and departure as one of the main motives for arrival, but as part of the program sells the whole of Dalmatia and it is an example of how destinations must cooperate. Especially Dubrovnik, which must use its media and financial power to sell and brand the wider area of ​​Dubrovnik, ie the entire Dubrovnik County as well as Dalmatia.center_img It is a journey that begins and ends in Dubrovnik, during which guests will also visit Ston, Makarska, Trogir and Split. He will spend two nights in Dubrovnik in the Dubrovnik hotels Hotel Rixos Libertas, Hotel Lero, Hotel Villa Paradiso and hotels from the Valamar group.  This year, over 30 visitors are planned to arrive by May 11, 2019, while next year the plan is to bring up to 65 visitors, according to the Dubrovnik Tourist Board.  Organized by the travel agency WTouristic, a member of the Karaci group and RSD Reisen from Germany, the winter program of senior group arrivals from Germany and Scandinavia with one charter per day starts on Monday, January 14, until February 11, when it will start arriving twice a day until 11:2018. .May. The winter program began in October XNUMX, after which it was briefly redirected to Split Airport due to works at the Dubrovnik airport.last_img read more

‘Maybe it’s working’: KPK says lack of raids thanks to successful prevention method

first_img“We will hold an evaluation meeting later. However, it doesn’t mean we are not doing anything [to fight corruption].”President Joko “Jokowi” Widodo inaugurated the three-star police general as KPK leader on Dec. 20 last year. Since then, the antigraft body has only launched two separate operations in January to arrest East Java’s Sidoarjo regent Saiful Illah and General Elections Commission (KPU) commissioner Wahyu Setiawan.However, the investigation of both cases started during the tenure of previous chairman Agus Rahardjo.Read also: KPK dumps cases as credibility slumps Corruption Eradication Commission (KPK) chairman Firli Bahuri said the commission’s lack of raids against state officials suspected of corruption might be thanks to the antigraft body’s success in preventing the special crime across the country.“Journalists asked me: ‘Why are there so few raids against corruption suspects?’ The answer is probably because our prevention method works,” Firli said on Wednesday as quoted by Antara news agency. Firli went on to say the KPK had three weapons in combating corruption: prevention, law enforcement and a combination of both. The KPK could implement preventive measures first, he said.“Our experience in investigating various corruption cases, ranging from goods and services procurement to public services, can be used to coordinate with ministries,” said Firli.He added he had visited several ministries, asking the ministers to map loopholes that could lead to corruption in their respective ministries.Read also: Synergy with other state institutions a ‘new soul’ of antigraft bodyThe chairman emphasized that the KPK’s first duty was to prevent corruption as stipulated in the revised KPK Law. The regulation took effect in October last year after the House of Representatives passed a revised bill following speedy deliberation.“Graft prevention could increase the government’s working performance. It will allow public services to work properly, and avoid high operational costs that lead to corruption.”Firli said he would organize a national corruption prevention act on March 31, in which various institutions – state ministries and regional administrations – would compete against each other in establishing a good system to prevent graft. (dpk)Topics :last_img read more

Sheffield United vs Arsenal TV channel, live stream, time, team news and odds

first_imgSheffield United vs Arsenal TV channel, live stream, time, team news and odds Metro Sport ReporterSunday 28 Jun 2020 10:14 amShare this article via facebookShare this article via twitterShare this article via messengerShare this with Share this article via emailShare this article via flipboardCopy link Comment Advertisement Advertisementcenter_img MORE: Chelsea handed Ben Chilwell boost as Ajax confirm Arsenal transfer target can goMORE: David Luiz took huge pay cut so Arsenal could complete Pablo Mari & Cedric Soares transfersFollow Metro Sport across our social channels, on Facebook, Twitter and Instagram.For more stories like this, check our sport page. Mikel Arteta is aiming for silverware in his first season as Arsenal manager (Picture: Getty Images)Sheffield United host Arsenal in the FA Cup quarter-finals on Sunday afternoon as they both look to become the second team into the semi-finals, where they will join Manchester United.It has been a difficult return from the coronavirus hiatus for both teams, with Sheffield United picking up just one point from three Premier League games, while the Gunners have won one game and lost two.Both sides’ push for European places appear to be forlorn, but they have the chance to focus on the cup this afternoon and secure a trip to Wembley.The other quarter-final contests on Sunday see Leicester host Chelsea and Newcastle face Manchester City.AdvertisementAdvertisementADVERTISEMENTWhat time is Sheffield United vs Arsenal?The match kicks-off at 1pm on Sunday 28 June at Bramall Lane.What TV channel is Sheffield United vs Arsenal on and is there a live stream?BT Sport 1 will be showing the game live with coverage starting at 12.30pm.Subscribers can stream the action on the BT Sport Player or BT Sport app.More: FootballRio Ferdinand urges Ole Gunnar Solskjaer to drop Manchester United starChelsea defender Fikayo Tomori reveals why he made U-turn over transfer deadline day moveMikel Arteta rates Thomas Partey’s chances of making his Arsenal debut vs Man CitySheffield United vs Arsenal team newsDean Henderson, John Egan and Jack O’Connell are all available for Sheffield United again.Arsenal are missing Bernd Leno, Gabriel Martinelli, Lucas Torreira, Pablo Mari, Calum Chambers and Cedric Soares is doubtful, but David Luiz returns from suspension.Sheffield United vs Arsenal odds11/5 Sheffield United9/4 Draw13/10 ArsenalOdds courtesy of Betfair Head-to-head in last five meetings 18 Jan 2020: Arsenal 1-1 Sheffield United – Premier League21 Oct 2019: Sheffield United 1-0 Arsenal – Premier League23 Sep 2008: Arsenal 6-0 Sheffield United – League Cup31 Oct 2007: Sheffield United 0-3 Arsenal – League Cup30 Dec 2006: Sheffield United 1-0 Arsenal – Premier Leaguelast_img read more

Watch to See How We Streamlined Mail Operations & Saved $1 Million

first_img SHARE Email Facebook Twitter Efficiency,  GO-TIME,  Government That Works,  The Blog,  Videos Yesterday, we announced that the Department of General Services transformed commonwealth agencies’ mail operations to save over $1 million. Our goal was to provide efficient and effective mail services without sacrificing quality.As this video explains, by consolidating presort operations in-house, we reduced state agency costs by two-thirds. Mail collection and delivery are now faster and more efficient and $1.069 million in savings has been achieved since the initiative began in November 2015That’s what happens when you approach a project like a business and put your customers – the people of Pennsylvania – first.Watch the video below to see how we made it all happen:Efforts through this initiative have saved more than $156 million in FY 15-16, exceeding the $150 million savings goal set by the governor. Governor Wolf is now challenging GO-TIME to build upon this success by achieving $500 million in savings by 2020. By: Curt Topper, Secretary of General Services December 09, 2016 Watch to See How We Streamlined Mail Operations & Saved $1 Million Like Governor Tom Wolf on Facebook: Facebook.com/GovernorWolf SHARE TWEETlast_img read more

Real estate: Gold Coast’s ‘forgotten suburbs’ booming

first_imgThe Gold Coast from the sky. (AAP Image/Dave Hunt)“We know values are rising on the Gold Coast and we know population growth is quite strong so I think it will continue to rise in line with population growth,” Mr Kusher said.“Interstate migration is ramping up and a lot of new supply has been built over the years.”But what will happen after the Commonwealth Games?“If you continue to see population growth, it’s reasonable to expect values to continue to rise,” Mr Kusher said.“It depends on migration and what happens to the stock including the Athlete’s Village, how quickly that comes on to the market.” Aerial view of a residential area on the Gold Coast. (AAP Image/Dave Hunt)“Bilinga is one of those areas that sometimes gets forgotten,” DJ Stringer Property Services principal David Stringer said.“You’ve got Tugun, Kirra and Coolangatta but Bilinga is the forgotten area.“When you look at the beachside of Bilinga you’re only 100m from the beach. It’s all about the value for money for buyers.”He said Bilinga’s location was proving popular with developers honing in on the suburb.“There’s a lot of good parcels of land with the old vintage flats which are ripe for developers,” he said. A Gold Coast aerial.Palm Beach (15.6 per cent rise), Elanora (15.4pc), Mermaid Beach (14.8pc), Tallebudgera Valley (14.3pc), Clear Island Waters (14.1pc), Lower Beechmont (14.0pc), Willow Vale (12.8pc) andBroadbeach Waters (12.7pc) rounded out the top 10.The report reveals nine out of 10 Gold Coast vendors made a profit on sales in the June quarter, pocketing almost $520 million.The median profit on the Gold Coast was $120,000 after holding a home for 7.9 years — $4000 up on the previous three months.CoreLogic research analyst Cameron Kusher said the 2018 Commonwealth Games and resulting construction boom as well as a growing population attributed to the strong property market. Aerial view of the Gold Coast.THE Gold Coast’s “forgotten suburbs” have emerged as top growth areas as homebuyers turn their attention towards the outskirts of the city.Figures released today reveal the relatively quiet suburbs of Bilinga and Elanora were among the top five to record the highest yearly growth for houses in the 12 months to June, 2017.It comes as buyers are pushed out of Palm Beach — another high-performing suburb that has recorded a massive 50 per cent jump in median house values over five years.The latest CoreLogic Pain & Gain report showed the median house value in Bilinga — the top performing suburb — was $587,335, up almost 19 per cent over 12 months. Bilinga.More from news02:37Purchasers snap up every residence in the $40 million Siarn Palm Beach North3 hours ago02:37International architect Desmond Brooks selling luxury beach villa23 hours agoGuanaba, a semirural suburb west of Maudsland and Mount Nathan, recorded the second highest house growth on the Coast with a 15.9 per cent jump over 12 months.Ray White Prestige Gold Coast agent Josh Thomas said the growth reflected some of the larger sales in the suburb.“The growth comes down to the fact it was really unknown until there were some substantial marketing on some of the larger properties,” Mr Thomas said.“I think that’s had a flow-on effect on the suburb.“It’s a beautiful part of the world and a lot of people are looking for that type of lifestyle — they’ve got the privacy and the land to accompany it.”last_img read more

Auction season tipped to start with a bang on Gold Coast

first_imgThe townhouse is in a lowset block positioned back from the beach.More from news02:37Purchasers snap up every residence in the $40 million Siarn Palm Beach Northless than 1 hour ago02:37International architect Desmond Brooks selling luxury beach villa20 hours agoThe fifth annual summer auction is set to be followed by a series of other auctions hosted by rival Gold Coast agencies.John Henderson Professionals Mermaid Beach principal Andrew Henderson said his team’s auction would set the benchmark for the other auctions to follow.“The real estate market on the Gold Coast has surged since 2016 and, with the Commonwealth Games fast approaching, we are hoping our Hot Summer Auction Event will kick off 2018 with a bang,’’ he said.“ … what is really impressive is the quality of the properties that we already have on offer.” The property has a private balcony and is close to the beach.Among the properties are a four-bedroom, three-bathroom waterfront home at Clear Island Waters, a five-bedroom, four-bathroom residence at Mermaid Beach, and a Miami beachfront townhouse.Mr Henderson, who was recently voted Gold Coast Zone Chairman for REIQ, said auctions have picked up dramatically in Queensland in the last decade due to increased vendor activity. This Miami townhouse will go to auction later this month. 31 Atlantic Ave, Mermaid Beach is also set to go under the hammer.center_img The two-level home was built just over a year ago. 2/86 Marine Pde, Miami is part of a bumper auction event on January 23.AUCTIONEERS’ gavels are warming up across the Gold Coast, with the region’s bumper summer auction season set to get underway this month.A dozen properties will go under the hammer as part of John Henderson Professionals Mermaid Beach’s ‘Hot Summer Auction Event’ on January 23.last_img read more

Track Aids

first_imgIt used to be that the only thing a kid had to improve his track performance was a starting block.  On the old cinder tracks they were heavy metal devices with spikes that stuck into the cinders.   Today these starting blocks are aluminum with very tiny spikes and the block is easy to adjusted to each sprinter.  Track races up through the 800 meters are so competitive that a good runner needs this push from the block to get the type of start that will give them a chance to win.  A good push from the blocks can give you as much as a 2-step lead in a sprint race.That brings me to some of the new devices used to improve the performances of track runners.  We use a ramp board in high jump to teach jumpers how to react to higher heights and improve their ability to arch their body over the bar.  In both high jump and pole vault, a band is used in practice instead of a crossbar.  This reduces the fear of coming down on a crossbar and injuring the jumper while they are learning the technique of these two events.  It also saves a lot of money since these bands seldom ever break.  If they do, they are inexpensive.There are all kinds of hurdle aids to again reduce injury in the novice hurdler and develop the proper step pattern in running a full set of hurdles.  These plastic devices are adjustable and do not impede the runner if he or she hits them.In another article I will talk about all the injury preventing aids that trainers now have to help runners.last_img read more

Batesville community traveling to Haiti

first_imgBATESVILLE, Ind. — 16 people from the Batesville community will be traveling to a village in Haiti to build homes for two different families.The 16 individuals have been busy raising the money needed for the trip and for building supplies.In all, the group has raised over $58,000.There will be two different teams making the trip.The first team will be in Haiti from March 25 – 31, while the second team will be there April 1 – 7.A Benefit concert with Mitch McVicker will be held on Wednesday, March 22, at 6:30 PM at the Batesville Christian Church to help raise the rest of the money needed for the trips.The team going to Haiti March 25 – 31 consists of Ashley Daulton, Lori Daulton, Mike Daulton, Drake Main, Elliot Main, Kip Main, Matthew Meehan, Tyler Ralston, Cooper Williams and MarDell Williams.The team going April 1 – 7 includes Gary Brower, Darren Cole, Laura Cole, Greg Fulkerson, John LaJeunesse and John Small.last_img read more

Gwynn flashes Hall numbers

first_imgI can remember the feeling of devastation as if it was yesterday. I was only eight and a diehard Milwaukee Brewers fan; I couldn’t comprehend what was going on.Major League baseball players were sitting out, and America’s pastime was shutting down. Being a Brewers fan was tough enough, and now baseball was stopping completely. I remember my dad trying to explain things like collective bargaining, salary caps and revenue sharing, but all of it sounded too strange. Why would these guys possibly stop playing baseball over a few dollars? They are baseball players! They have the best job imaginable. I would play for free!The net result of that 1994 MLB strike was the first canceled World Series in 90 years, managing to do what two world wars could not.So why is the strike important now, in the middle of baseball’s offseason, 13 years later? The Baseball Hall of Fame recently concluded balloting for its 2007 class, and headlining the ballot were Cal Ripken Jr., Tony Gwynn and Mark McGwire, a trio who dominated the ’90s baseball landscape, albeit in quite different ways: McGwire’s prodigious power led a league-wide power surge in the second half of the ’90s, Ripken’s durability allowed him to play every game for the first nine years of the decade, and Gwynn’s sweet swing led the National League in batting four times.The media reaction to the balloting results — which saw Gwynn and Ripken elected to the Hall of Fame with historic consensuses and McGwire falling far short of the 75 percent approval required for induction — oddly mirrored the attention each player received while he built his Hall résumé. The media attention surrounding McGwire when he was bashing fastballs farther than some puddle-jumping airplanes fly returned again on a lesser scale. This time, the focus was not on how many homers he popped into the stands, but instead on how many steroids or supplements he may have popped into his mouth.Ripken was expected to be there when the inductees were announced — the only question was how large of a percentage he would receive. Similarly, he was expected to be there every day when the starting lineups were announced — the only question was for how long he would last.Gwynn received very little attention. As a player, all Gwynn did was hit. A lot. Not long, towering shots like McGwire. Not every day like Ripken. In the SportsCenter era, Gwynn specialized in hitting singles — the least flashy play in baseball. Gwynn went about his business largely under the radar. When it came to the Hall discussion this year, Gwynn was the somewhat forgotten one, stuck playing third fiddle behind McGwire and Ripken. The three are all so closely tied to the strike-shortened season and its aftermath. McGwire and Ripken are largely credited with resuscitating MLB after the strike, and rightly so. The feel-good story of Ripken playing in every game for sixteen seasons mirrored how the average person showed up and worked every day. And the home run chase for Roger Maris’ single season home run record between McGwire and Sammy Sosa captivated the nation during the 1998 season.Gwynn’s tie to the strike is at the root of why he may be a less recognized player despite winning eight batting titles over his 20-year career. In a game where numbers and stats are king, and tradition is cherished, that ’94 strike-shortened season saw Gwynn take on an assault of the most elusive number in baseball: the .400 batting average. When the strike ended the season Aug. 12, 1994, Gwynn’s average sat at .394. It doesn’t get much closer than that. Had only three bloopers gone uncaught or three grounders found holes in the infield, Gwynn would have had his .400.Had the season continued, there is a definite possibility he would have raised his average six hundredths of a point and finished with the first .400 season since Ted Williams in 1941. As it stands now, Gwynn is the last hitter to seriously challenge for a .400 season (The highest average to finish a season since ’94 was Larry Walker’s .379 in ’99). If only Gwynn had reached that mark, his ’94 season would never have been forgotten. Gwynn would then almost certainly be one of the first players mentioned when the best hitters of all time are discussed. Instead, he may end up as an afterthought, as unfair as it may be. But there was much more to Gwynn’s game than just a productive left-handed stroke. Gwynn actually was quite the defensive player too, early in his career, winning five Gold Gloves between ’86 and ’91. As his career continued, knee and weight issues limited his mobility in the outfield and on the base paths. Fans who recall only the Gwynn of latter years may be surprised to find out that a younger, trimmer Gwynn was actually a prolific base stealer. Over a six-year span from ’84 to ’89, Gwynn stole an average of 34 bases a season, peaking with a 56-steal season in ’87.Perhaps part of the reason Gwynn is often overlooked is because he played a quiet game. He wasn’t especially flashy, didn’t hit a lot of home runs and wasn’t one for long streaks — his career long hit streak was only 25 games. In comparison, there have been 46 streaks of 30 games or longer in MLB history, including a 32-gamer in 1997 by some guy named Hal Morris.But Gwynn wasn’t just a baseball player. While at San Diego State, he also starred for the Aztecs on the basketball court as the team’s point guard, where he still holds records for most assists in a season (221) and most assists in a career (590, held by a margin of nearly 200). He also ranks third all-time at the school for steals. And talk about your good days! On the same day as the Padres made Gwynn the 58th overall selection in the MLB draft, the Clippers chose him in the 10th round of the NBA draft.Not surprisingly, not many people remember that either.Ben is a sophomore majoring in political science and journalism. Send your thoughts about Gwynn, the Hall of Fame or the strike to bvoelkel@badgerherald.com.last_img read more